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March 7, 2007
Combination Of Green Tea And COX-2 Inhibitors Slow Prostate Cancer
Topics: Prostate Cancer
Drinking warm green tea has long been touted for its healthful benefits, both real and anecdotal. But now researchers have found that a component of green tea, combined with low doses of Celecoxib, a COX-2 inhibitor (drugs for inflammation that selectively block the COX-2 enzyme), could slow the spread of human prostate cancer:
... In the March 1 issue of Clinical Cancer Research, researchers from University of Wisconsin-Madison demonstrate that low doses of the COX-2 inhibitor celecoxib, administered with a green tea polyphenol called Epigallocatechin-3-gallate (EGCG), can slow the growth of human prostate cancer. Their experiments were performed in cell cultures and in a mouse model for the disease.... Celecoxib and green tea have a synergistic effect -- each triggering cellular pathways that, combined, are more powerful than either agent alone ...
... "Our studies showed that the additive effect of green tea enables us to utilize the cancer-fighting abilities of COX-2 inhibitors, but at lower, safer doses."
Posted by Richard at March 7, 2007 12:51 AM
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