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November 2, 2007

Mechanism Found To Predict Lung Cancer Survival In Women

Topics: lung cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center have discovered a link between increased levels of aromatase, an enzyme that naturally makes estrogen from another hormone called androgen, to more aggressive disease and lower survival rates in women over 65 with Stage 1 or 2 lung cancer.

The discovery not only gives physicians a possible new tool to predict survival but may also provide a target for therapy using aromatase inhibitors, already approved for the treatment of breast cancer.
More at Science Daily ....

Currently, there are three aromatase inhibitors approved by the U.S. Food and Drug Administration: anastrazole (Arimidex®), exemestane (Aromasin®), and letrozole (Femara®).

Related: Links to NCI materials on aromatase inhibitors ...

Posted by Richard at November 2, 2007 5:35 PM

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